At least 45 people were confirmed dead in recent clash between the pro-government forces and jihadist-led groups on Tuesday, a war monitor said.
According to the Syrian Observatory Human rights, the fight started on the edge of Hama province when jihadist group Hayat Tahrir al-Sham launched a dawn attack on regime positions.
At least 14 pro-government forces died in ensuing clashes, said the Britain-based monitor.
State news agency SANA also said the offensive had been thwarted.
Hama’s northern countryside lies on the edge of a jihadist-controlled region including most of Idlib province.